Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction

Abstract

Abdominal wall defects, including hernias and congenital anomalies, are complex conditions that require practical and durable repair strategies. While commonly used, traditional synthetic meshes often face limitations such as poor integration with host tissue and complications like infection or adhesion formation. This paper presents hydrogel-based materials as a novel approach to addressing these abdominal wall defect repair challenges. Hydrogels, characterized by their biocompatibility, tunable mechanical properties, and ability to support tissue regeneration, offer a promising alternative to existing methods. This paper explores the design and application of these hydrogels, highlighting their potential to improve surgical outcomes through enhanced tissue integration, reduced inflammation, and minimized postoperative complications. Preclinical and clinical evidence suggests that hydrogel technology could revolutionize the standard of care for abdominal wall defects, offering a more effective and patient-friendly solution.